Michelle Dede was born on 23 March in Germany, to the family of Brownson Dede, a Nigerian diplomat and former ambassador to Ethiopia. She had her early education in Brazil, her secondary and high school education was completed in Australia and Ethiopia respectively. She later proceeded to the United Kingdom to study Fashion Design and Marketing at the American College in London, the U.K. She also holds a post-graduate degree in Communications and P.R from the same institution.
Her career started following a holiday in Nigeria. In 2006, alongside Olisa Adibua, she co-hosted the debut edition of Big Brother Nigeria, a Nigerian television series based on the Big Brother series. She later co-produced the 2013 film Flower Girl before she went on to star as Tari Gambadia in the TV series Desperate Housewives Africa. She cites Oprah Winfrey as her inspiration as a T.V host. In 2017, Dede starred in the Nigerian drama thriller film What Lies Within with Paul Utomi, Kiki Omeili and Tope Tedela. In 2018 she starred in Moms at War
